Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Computer models may unlock personalized AFib treatment

NCT ID NCT05057507

Knowledge-focused Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study enrolled 91 people with atrial fibrillation to see if computer simulations can identify the main electrical problem causing their irregular heartbeat. Participants had heart imaging, mapping, and symptom tracking before and after a standard ablation procedure. The goal is to move beyond simple duration-based categories and toward mechanism-based treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to more personalized treatments for atrial fibrillation by identifying the specific electrical mechanism in each patient.
What could go wrong
This is an observational study with no direct treatment being tested, so it will not immediately change care. The computational models may not translate into better outcomes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

91 people

The number who actually took part.

Started

Jan 2022

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Up to 115 patients undergoing electrophysiological assessment will be recruited with inclusion and exclusion criteria as indicated above.

Ages

18 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Symptomatic paroxysmal atrial fibrillation or persistent atrial fibrillation diagnosed - within 24 months preceding the consent date. * Planned radiofrequency ablation for atrial fibrillation consisting of pulmonary vein isolation. * Able and willing to comply with study follow-up requirements * Able and willing to provide written informed consent Exclusion Criteria: * Any clinical contra-indication to ablation * Any disease limiting life expectancy to \< 1year * Contra-indication to MRI including renal dysfunction (eGFR\<30ml/min) * Potential participant currently pregnant or breast feeding * Prior ablation, cardiac surgery or presence of any prosthetic valves * Myocardial infarction or percutaneous coronary intervention within 3 months preceding consent date * Hypertrophic cardiomyopathy or other inherited cardiac condition * Presence / likely implant of any pacemaker, cardiac resynchronization therapy device or implantable defibrillator within 1 year * Enrolment in an existing interventional atrial fibrillation study which alters treatment or follow-up. * Use of amiodarone for any indication within 6 months prior to the planned ablation procedure * Use of any anti-arrhythmic drug for an arrhythmia indication other than atrial fibrillation * Prior documented cavotricuspid isthmus dependent right atrial flutter and planned cavotricuspid isthmus ablation to be performed at the time of atrial fibrillation ablation * Unable to understand verbal or written explanations given in English or German as appropriate.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Atrial fibrillation are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation

Contacts and locations

Locations

  • Guy's and St Thomas' NHS Foundation Trust

    London, United Kingdom

  • NHS Lothian

    Edinburgh, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.