Scientists hunt for heart rhythm genes in 1,300 patients
NCT ID NCT00599118
First seen Jun 26, 2026 · Last updated Sep 15, 2026 · Updated 2 times
Summary
This study aims to uncover the genetic roots of atrial fibrillation, a common heart rhythm disorder. Researchers are collecting blood samples and health data from 1,300 adults—some with the condition and some without—to compare their DNA. The goal is to identify genetic variants that may increase the risk of developing atrial fibrillation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify genes that increase the risk of atrial fibrillation, pointing toward better prevention or treatment strategies in the future.
- What could go wrong
- This is an observational study that does not test any treatment. It may not find clear genetic links, and any potential benefits are far off.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2005
- Expected to finish
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Dec 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects with atrial fibrillation
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for Atrial Fibrillation group: * Male or female at least 18 years old * Subjects with a history of or current Atrial Fibrillation * Subjects able to give informed consent Exclusion Criteria for Atrial Fibrillation group: no history of atrial fibrillation Inclusion Criteria for Controls: * Male or female at least 18 years old * Subjects with no history of Atrial Fibrillation * Subjects able to give informed consent Exclusion Criteria for controls: History of atrial fibrillation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinical Foundation
Cleveland, Ohio, 44145, United States
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