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Hidden blood pressure gap in shock could mislead treatment

NCT ID NCT06460519

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 18, 2026 · Updated 3 times

Summary

This study aims to find out how often a blood pressure difference between the arm and leg occurs in patients with shock. Researchers will measure blood pressure non-invasively in 180 adults receiving strong vasopressors. The goal is to understand this gap better, so doctors can avoid giving incorrect doses of blood pressure medicines.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better monitor blood pressure in shock patients, potentially leading to safer use of vasopressors.
What could go wrong
This is an observational study, not a treatment trial. It only measures a phenomenon, so it won't directly improve patient outcomes. Results may not apply to all shock types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

180 patients of intensive care unit (ICU), in shock with equal or more than 0.5µg/kg/min of norepinephrine equivalent, who are not in perioperative of cardiac surgery. And who have a monitoring of arterial pressure by a radial catheter, and for who the physician decided to put in place a femoral arterial catheter.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age superior or equal 18 years * Vasopressors support superior or equal 0.5 µg/kg/min of equivalent norepinephrine * Invasive monitoring of blood pressure with a radial arterial catheter and a femoral arterial catheter decided by de physician * Beginning of the shock less than 48 hours. * Consent Exclusion Criteria: * perioperative of cardiac surgery (between the beginning of the surgery and 7 days after) * pregnant woman or breast-feeding * Major person under protection * Person with privation of liberty by a justice decision, or an administrative decision

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Conditions

The condition(s) this trial relates to.

Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Shock

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre hospitalier Lyon Sud/Groupement hospitalier Sud, Service d'anesthésie réanimation médecine intensive

    RECRUITING

    Lyon, 69495, France

  • Département d'anesthésie Réanimation Hôpital Cardiologique Louis Pradel/Groupement Hospitalier Est

    RECRUITING

    Bron, 69500, France

  • Département d'anesthésie-réanimation CHU de Clermont-Ferrand

    RECRUITING

    Clermont-Ferrand, 63000, France

  • Hopital Edouard heriot/Groupement hospitalier Centre, service de médecine intensive réanimation

    RECRUITING

    Lyon, 69003, France

  • Hôpital Edouard Heriot/ Groupement hospitalier Centre, service d'anesthésie réanimation

    RECRUITING

    Lyon, 69003, France

  • Hôpital Saint Joseph Saint Luc

    RECRUITING

    Lyon, 69007, France

  • Hôpital de la Croix-Rousse/Groupement hospitalier Nord, service d'anesthésie réanimation

    RECRUITING

    Lyon, 69004, France

  • Service d'Anesthésie Association hospitalière Protestante de Lyon

    RECRUITING

    Lyon, 69000, France

  • Service de réanimation médico-chirurgicale et traumatologique Centre Hospitalier Universitaire de la Guadeloupe

    RECRUITING

    Les Abymes, Guadeloupe

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