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Could a leukemia drug help fight breast cancer? new trial investigates

NCT ID NCT04113863

First seen Dec 26, 2025 · Last updated Jun 08, 2026 · Updated 31 times

Summary

This study tested whether adding a drug called ATRA (all-trans retinoic acid) to the standard hormone therapy anastrozole could shrink tumors more effectively in postmenopausal women with a common type of early breast cancer (HR-positive/HER2-negative). The trial was planned for 76 participants and took place before their scheduled surgery. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASST Papa Giovanni XXIII

    Bergamo, 24127, Italy

  • Ospedale Santa Maria della Misericordia di Udine

    Udine, UD, 33100, Italy

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.