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New combo therapy aims to shrink tumors in hard-to-treat cancers

NCT ID NCT03915678

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 31 times

Summary

This study is testing whether adding an immune-boosting drug (BDB001) and targeted radiation to the immunotherapy atezolizumab can help control or shrink tumors in people with advanced solid tumors, including pancreatic, lung, bladder, and breast cancers. About 247 adults with these cancers will receive the combination treatment. The main goal is to see how many patients have their disease controlled (shrink or stay stable) within 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CHU Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact Email: •••••@•••••

  • Centre Eugène Marquis

    RECRUITING

    Rennes, 35042, France

    Contact Email: •••••@•••••

  • Centre François Baclesse

    RECRUITING

    Caen, 14076, France

    Contact Email: •••••@•••••

  • Centre Georges François Leclerc

    RECRUITING

    Dijon, 21079, France

    Contact

    Contact

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59020, France

    Contact

    Contact

  • Chu Brest

    RECRUITING

    Brest, 29200, France

    Contact

    Contact

  • Hôpital La Timone

    NOT_YET_RECRUITING

    Marseille, 13005, France

    Contact Email: •••••@•••••

  • IUCT Oncopôle

    RECRUITING

    Toulouse, 31052, France

    Contact

    Contact

  • Institut Bergonié

    RECRUITING

    Bordeaux, 33076, France

    Contact Email: •••••@•••••

  • Institut Curie

    NOT_YET_RECRUITING

    Paris, 75005, France

    Contact

    Contact

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, 13273, France

    Contact

    Contact

Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm melanoma neoplasm Neoplasm Metastasis non-small cell lung carcinoma pancreatic neoplasm soft tissue sarcoma triple-negative breast carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms virus associated tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.