Eye injection could replace corneal transplant for blinding swelling
NCT ID NCT07368959
First seen Jan 31, 2026 · Last updated May 25, 2026 · Updated 16 times
Summary
This study tests a single injection of AURN001 in 120 adults with corneal swelling (edema) caused by endothelial dysfunction, including Fuchs' dystrophy. The goal is to see if the injection improves vision by at least 3 lines on an eye chart and reduces corneal thickness at 6 months, compared to a placebo. Participants must already have an artificial lens and be candidates for corneal transplant surgery.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Investigational Site 1
RECRUITINGSpring, Texas, 77388, United States
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Investigational Site 10
RECRUITINGPlymouth Meeting, Pennsylvania, 19462, United States
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Investigational Site 11
RECRUITINGLeland, North Carolina, 28451, United States
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Investigational Site 12
RECRUITINGLadson, South Carolina, 29456, United States
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Investigational Site 2
RECRUITINGMesa, Arizona, 85206, United States
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Investigational Site 3
RECRUITINGCynwyd, Pennsylvania, 19004, United States
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Investigational Site 4
RECRUITINGKansas City, Missouri, 64154, United States
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Investigational Site 5
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Investigational Site 6
RECRUITINGLittle Rock, Arkansas, 72205, United States
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Investigational Site 7
RECRUITINGAtlanta, Georgia, 30339, United States
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Investigational Site 8
RECRUITINGSan Antonio, Texas, 78209, United States
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Investigational Site 9
RECRUITINGFort Collins, Colorado, 80528, United States
Conditions
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