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Aspirin may stop Barrett's esophagus relapse, early trial hints

NCT ID NCT02521285

First seen Sep 30, 2025 · Last updated May 22, 2026 · Updated 20 times

Summary

This early-phase study tests whether taking aspirin can prevent Barrett's esophagus from returning after it has been successfully removed with a procedure called radiofrequency ablation. About 21 participants will take either aspirin or a placebo for 12 months, and researchers will measure certain proteins in tissue samples to see if aspirin reduces the risk of recurrence. The goal is to find a safe, simple way to keep the condition from coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston, Texas, 77030, United States

  • Kansas City Veterans Affairs Medical Center

    Kansas City, Missouri, 64128, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Saint Michael's Hospital

    Toronto, Ontario, M5B 1W8, Canada

  • UCHealth University of Colorado Hospital

    Aurora, Colorado, 80045, United States

  • UCLA / Jonsson Comprehensive Cancer Center

    Los Angeles, California, 90095, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.