Higher aspirin dose may better protect pregnant women from dangerous hypertension
NCT ID NCT06468202
First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tests whether taking 162 mg of aspirin daily is better than the standard 81 mg dose for preventing high blood pressure disorders (like preeclampsia) in pregnant women at risk. Over 10,000 participants will be assigned to one of the two doses early in pregnancy. The goal is to find the most effective dose to reduce serious complications for both mother and baby.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PREECLAMPSIA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Brown University
RECRUITINGProvidence, Rhode Island, 02905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
-
Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
Contact
Contact
Contact Email: •••••@•••••
-
Columbia University
RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Eastern Virginia Medical School - Old Dominion University
RECRUITINGNorfolk, Virginia, 23501, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
Inova HealthSystem
RECRUITINGFalls Church, Virginia, 22042, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
-
Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Contact
-
The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine
RECRUITINGColumbus, Ohio, 43210, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of California, San Francisco
RECRUITINGSan Francisco, California, 94158, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
University of Mississippi
RECRUITINGJackson, Mississippi, 39216, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact
-
University of New Mexico
RECRUITINGAlbuquerque, New Mexico, 27710, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
University of North Carolina, Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact
-
University of Pittsburg Magee
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
University of Texas, Houston
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Aspirin (81 mg or 162 mg daily)
What this could lead to
If it works, this could show that a higher aspirin dose is better at preventing dangerous pregnancy complications like preeclampsia, potentially saving lives.
What could go wrong
This is a large trial, but results may not apply to all populations. Aspirin can cause side effects like bleeding, and the higher dose may not be more effective or could increase risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.