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Herbal hope: ashwagandha supplement put to the test for weight loss and stress relief

NCT ID NCT07215455

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a daily 300 mg dose of KSM66 ashwagandha root extract can help overweight and obese adults manage their weight and stress. Fifty participants took either the supplement or a placebo for 8 weeks. Researchers measured changes in body weight, BMI, and perceived stress levels to see if the herb makes a real difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ashwagandha root extract (KSM66)
What this could lead to
If it works, this could point toward a natural supplement option for supporting weight management and reducing stress in overweight adults.
What could go wrong
This is a small, completed trial with only 50 participants, so results may not apply to everyone. As a dietary supplement, effects are likely modest and not a substitute for diet and exercise.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Jun 2025

Finished

Oct 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Healthy adult men and women participants ≥ 19 years and ≤65 years of age. 2. Willingness to follow the protocol requirements as evidenced by written informed consent. 3. Participants willing to give meaningful, written informed consent prior to participation in the trial, in accordance with regulatory requirements. 4. Participants who agree to take investigational product (i.e., Till Week 8). 5. Participants with Body mass index between 25 and 39.9 kg/m2 Exclusion Criteria: 1. History of Alcohol or smoking abuse. 2. History of hypersensitivity to Ashwagandha 3. Taking nutritional or energy supplements, medication, or steroids, 4. Any history of drug abuse 5. Having any clinical abnormalities 6. Simultaneously participating in any other clinical trial or participated in the past three months 7. Participants who use medication for blood pressure, use beta-blockers, inhaled any beta-agonists, use any hormonal contraceptives, having a history of corticosteroid use within three months, participants under psychotropic medication within last 8 weeks 8. Participants diagnosed with any heart disease, diabetes, stroke, neurological disorders or depression. 9. Have clinically significant acute unstable hepatic, renal, cardiovascular, or respiratory disease that will prevent participation in the study. 10. Patients with depressive episode, panic disorder, social phobia, obsessive-compulsory disorder, alcohol dependency; schizophrenia and mania. 11. Patients with post traumatic disorder. 12. Have an established practice of meditation (as meditating for at least 20 minutes, three or more times per week) for three or more months. 13. Pregnant and lactating women 14. Participation in other clinical trials during previous 3 months 15. Any clinical condition, according to the investigator which does not allow safe fulfilment of clinical trial protocol.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • San Francisco Research Institute

    San Francisco, California, 94132, United States

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