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Sourdough bread may soothe tummy troubles for bread-sensitive folks

NCT ID NCT07568223

Symptom relief Sponsor: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether eating a special artisanal bread made with whole wheat flour and sourdough can reduce stomach discomfort in people who usually feel sick after eating regular bread. Forty adults who are intolerant to conventional bread but do not have celiac disease will eat the artisanal bread for 15 days. Researchers will compare their gut symptoms before and after the diet to see if the artisanal bread is better tolerated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Normal weight (18 \< BMI \< 25 kg.m-2) * Male or female * 18 to 65 years old * Adults reporting intolerance to "conventional" bread * Absence of celiac disease * Affiliated to a social security scheme * Free, informed and express consent Exclusion Criteria: * People under protective supervision: legal guardianship, tutorship or curatorship * People with eating disorders (anorexia, bulimia, binge eating) * Any known food allergy * Women who are pregnant or potentially pregnant (based on a positive urine pregnancy test at inclusion) * Breastfeeding women * Alcohol abuse (\>2 drinks/day). At the time of inclusion, the investigator will assess whether the participant exhibits harmful alcohol consumption * Untreated hypertension, uncontrolled diabetes, or diseases of the digestive tract (excluding functional intestinal disorders), liver, kidneys, or severe heart disease. The investigator will assess the presence of these conditions on standard clinical criteria and the participants' self-reported medical history at the time of inclusion * Participation in a clinical study in the three months preceding the study * Absence of express consent

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Conditions

The condition(s) this trial relates to.

celiac disease Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intolerance to "conventional" bread

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre de Recherche sur Volontaires

    RECRUITING

    Bobigny, 93000, France

  • Centre de Recherche sur Volontaires (CRV)

    NOT_YET_RECRUITING

    Bobigny, Île-de-France Region, 93000, France