New study aims to crack Tough-to-Diagnose joint diseases
NCT ID NCT06312943
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is collecting joint fluid and tissue samples from 50 adults with inflammatory or non-inflammatory bone and joint diseases. Researchers will use both standard and advanced lab techniques to find new biomarkers that could help diagnose rheumatic diseases more accurately and earlier, especially in cases where current methods fail.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to more accurate and earlier diagnoses for hard-to-classify rheumatic diseases.
- What could go wrong
- This is a small, early-stage observational study (50 participants) focused on lab analysis, not a treatment trial. The new methods may not prove reliable enough for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Aug 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
¨Patients with various bone and joint diseases
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Inflammatory and non-inflammatory bone and joint diseases requiring synovial fluid aspiration and/or joint replacement * Collection of non-opposition * Affiliated to or beneficiary of social security Exclusion Criteria: * Inability to speak and/or read French * Neoadjuvant therapy * Patients under tutor or curatorship * Protected adults, * Patients benefiting of State Medical Aid
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Service de Médecine Physique et de Réadaptation, Hôpital Cochin
RECRUITINGParis, IDF, 75014, France
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