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Sniff your way to better rehab? aromatherapy patches tested in hospital study

NCT ID NCT05282706

Symptom relief Sponsor: The University of Texas Health Science Center at San Antonio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether wearing aromatherapy patches with lavender, mandarin, or peppermint oil could reduce pain and nausea in hospital patients during physical or occupational therapy. 165 adults in an acute care setting were randomly assigned to receive an aromatherapy patch or a placebo patch. The goal was to see if the scents helped patients complete their therapy sessions and feel better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aromatherapy patches (lavender, mandarin, or peppermint oil)
What this could lead to
If it works, this could offer a simple, drug-free way to help patients feel better during therapy and possibly shorten hospital stays.
What could go wrong
This is a small, early-phase study, so results may not be conclusive. The effect might be due to the placebo effect, and people with respiratory conditions were excluded.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

165 people

The number who actually took part.

Started

May 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Inpatients of acute care setting at University Health hospital 2. Provision of a signed and dated informed consent form 3. English or Spanish speaking 4. Male or Female, aged 18 years and older 5. Willing to comply with all study procedures Exclusion Criteria: 1. Respiratory disorders, e.g., asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, lung cancer, cystic fibrosis, pneumonia, pleural effusion 2. Cognitive impairment 3. Unable to communicate 4. Admitted to the closed access unit or to psychiatry 5. Allergic to lavender, mandarin or peppermint oil 6. Diseases that cause olfactory disorders such as: COVID-19, benign growths or polyps, congestion from a cold, sinus infection or allergy flare-up 7. Drugs that may cause loss of the ability to smell e.g., intranasal zinc products, decongestant nose sprays and certain oral drugs such as nifedipine and phenothiazines 8. Pregnant women (self-reported) 9. Prisoner

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Conditions

The condition(s) this trial relates to.

Nausea Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nausea Suffering, physical

Contacts and locations

Locations

  • Bianca Gonzales

    San Antonio, Texas, 78253, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.