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Could a simple shot replace IV drips for nausea?

NCT ID NCT02466984

First seen May 20, 2026 · Last updated Jun 19, 2026 · Updated 7 times

Summary

This study looked at whether metoclopramide, a common anti-nausea drug, works as well when injected under the skin (subcutaneous) as when given through a vein (IV). Five patients in a palliative care unit received the drug both ways to compare absorption. The goal is to offer a more comfortable and convenient option for managing nausea and vomiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Bordeaux - St André

    Bordeaux, Aquitaine, 33000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

metoclopramide (Primperan)

What this could lead to

If it works, this could provide a simpler, less invasive way to give metoclopramide for nausea and vomiting in patients who cannot take oral medication.

What could go wrong

This is a very small study (5 participants) in a specific palliative care setting, so results may not apply broadly. The drug's effectiveness via subcutaneous route is still unproven.

Conditions

The condition(s) this trial relates to.

Nausea Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.