Could a simple shot replace IV drips for nausea?

NCT ID NCT02466984

Completed Symptom relief Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether metoclopramide, a common anti-nausea drug, works as well when injected under the skin (subcutaneous) as when given through a vein (IV). Five patients in a palliative care unit received the drug both ways to compare absorption. The goal is to offer a more comfortable and convenient option for managing nausea and vomiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: metoclopramide (Primperan)
What this could lead to: If it works, this could provide a simpler, less invasive way to give metoclopramide for nausea and vomiting in patients who cannot take oral medication.
What could go wrong: This is a very small study (5 participants) in a specific palliative care setting, so results may not apply broadly. The drug's effectiveness via subcutaneous route is still unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NAUSEA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Nausea Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NAUSEA VOMITING

Contacts and locations

Locations

Centre Hospitalier Universitaire de Bordeaux - St André

Bordeaux, Aquitaine, 33000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.