Arm cuff trick may shield Seniors' lungs after surgery
NCT ID NCT07208500
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a simple, non-invasive procedure called Remote Ischemic Preconditioning (RIPC) can reduce lung complications like pneumonia in adults aged 65 and older after non-cardiac, non-chest surgery. Participants will have a blood pressure cuff inflated on their arm 24 hours before surgery in a series of short cycles. The goal is to see if this gentle stimulation activates the body's natural defenses and lowers the risk of postoperative lung problems.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Remote Ischemic Preconditioning (RIPC) procedure using a blood pressure cuff
- What this could lead to
- If it works, this simple, low-cost procedure could become a standard way to protect older patients' lungs after surgery.
- What could go wrong
- This is an early-stage study with 390 participants, so results may not apply to everyone. The procedure may cause temporary arm discomfort or bruising.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 390 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Elderly patients aged 65 years and above undergoing non-cardiac and non-thoracic surgery; operation time of 1-3 hours; American Society of Anesthesiologists (ASA) classification from I to II; BMI of 18-30 kg/m². Exclusion Criteria: * NYHA cardiac function classification is grade II to IV; there is severe respiratory dysfunction before surgery; there is a history of coagulation dysfunction diseases; chemotherapy, radiotherapy or immunotherapy have been received within 3 months; there is systemic or local active infection; there is peripheral vascular disease affecting upper limb blood vessels; antibiotics, non-steroidal anti-inflammatory drugs, or corticosteroids have been taken within the past 3 months.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shanghai Geriatric Medical Center
RECRUITINGShanghai, China
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