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Early drug test aims to tackle root cause of rare lung and liver disease

NCT ID NCT02363946

Summary

This early-stage study tested a new drug called ARC-AAT in healthy volunteers and people with Alpha-1 Antitrypsin Deficiency (AATD). The main goal was to check if the drug was safe and to see if a single dose could lower the levels of a harmful protein in the blood that causes lung and liver damage in AATD. The study was terminated, and it was not designed to see if the drug improves symptoms or is a cure.

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Contacts and locations

Locations

  • Research Site 1

    Melbourne, Victoria, 3004, Australia

  • Research Site 2

    Homburg, Germany

  • Research Site 3

    Leiden, 2333ZA, Netherlands

  • Research Site 4

    Edgbaston, Birmingham, B15 2WB, United Kingdom

Conditions

Explore the condition pages connected to this study.