Could AR games beat the patch? new study tests lazy eye treatment in teens and adults

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals aged 12 to 55 years (12 ≤ age ≤ 55 years). Written informed consent shall be obtained from participants aged 18 years and above, or their legal guardians for those aged 12 to 17 years. 2. Unilateral amblyopia with the following criteria: the best-corrected visual acuity (BCVA) of the dominant eye ≥ 0.8, and an interocular BCVA difference of two or more lines. Participants shall have confirmed amblyopia with relevant risk factors and no organic ocular diseases. 3. For Individuals with refractive errors: the spherical equivalent (SE) measured via cycloplegic autorefraction or phoropter refraction ≤ -6.00 D. All participants shall have received optical refractive correction for more than 3 months, with stable visual acuity (acuity change \< 1 line) within the latest 2 months. 4. Individuals with orthotropic eye position, including patients with strabismic amblyopia after strabismus correction. The distance manifest deviation measured at 6 m using the prism and alternate cover test shall be within 5 prism diopters (△). 5. Individuals who are willing to enroll in this study and are able to complete the entire trial protocol. Exclusion Criteria: 1. Participants with other organic ocular disorders, including media opacities, nystagmus, eccentric fixation, acute inflammatory conditions such as keratitis, optic neuropathy, including glaucoma, retinal lesions, and cortical visual impairment. 2. Individuals diagnosed with tumors, cardiac diseases, hypertension, or epilepsy. 3. Individuals with implanted electronic devices such as cardiac pacemakers. 4. Individuals presenting with severe ocular inflammation, photophobia, or lacrimation in either eye. 5. Individuals with a history of ocular surgery that affects visual function, excluding congenital cataract extraction combined with intraocular lens implantation, strabismus correction and blepharoptosis repair. 6. Individuals with severe mental disorders or poor treatment adherence. 7. Individuals currently using or planning to use medications that may affect visual function (mydriatic eye drops for refraction examination such as atropine are excluded). 8. Individuals with diplopia or inability to achieve binocular fusion during augmented reality-based amblyopia training. 9. Individuals who received any amblyopia treatments except spectacle lenses within 2 weeks prior to screening. 10. Individuals who enrolled in other clinical drug trials within 3 months or other medical device trials within 1 month before recruitment. 11. Individuals who are unable to attend regular ophthalmological examinations. 12. Individuals deemed ineligible by the investigators.