New hope for Hard-to-Treat cancers: experimental drug APL-5125 enters human trials
NCT ID NCT06399757
First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 13 times
Summary
This study tests a new drug called APL-5125 in adults with advanced solid tumors, including colorectal, pancreatic, and breast cancers. The goal is to see if the drug is safe and can shrink or control tumors. About 100 participants will receive the drug in two phases, first to find the right dose and then to measure its effect on colorectal cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Carolina BioOncology Institute
RECRUITINGHuntersville, North Carolina, 28078, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope
ACTIVE_NOT_RECRUITINGDuarte, California, 91010, United States
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City of Hope Orange County Lennar Foundation Cancer Center
ACTIVE_NOT_RECRUITINGIrvine, California, 92618, United States
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Duke Cancer Institute
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Florida Cancer Specialists & Research Institute
RECRUITINGSarasota, Florida, 34232, United States
Contact Email: •••••@•••••
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Mary Crowley Cancer Research
RECRUITINGDallas, Texas, 75251, United States
Contact Email: •••••@•••••
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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NEXT Oncology- San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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