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Scientists use video and sensors to objectively measure apathy

NCT ID NCT03272230

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to create a better way to measure apathy—a lack of motivation and goal-directed behavior—in people with brain diseases like frontotemporal dementia and depression. Researchers used video recordings and body sensors to track behaviors in a real-life setting. 66 healthy volunteers and patients participated. The goal was to develop an objective diagnostic tool to identify and quantify apathy, which could lead to more tailored treatments in the future.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Sep 2017

Finished

May 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Eligibility Criteria for All Groups: * Demonstrates the ability to provide informed consent for participation in the study. * Capable of understanding study instructions and performing cognitive tasks as required. * Enrolled in a valid health insurance plan. Eligibility Criteria for Patients: * Mini-Mental State Examination (MMSE): Score ≥ 17. * Medical History: Absence of any other neurological or psychiatric conditions. * Caregiver Requirement: Must have a caregiver present. Patient Groups: * Diagnosed with behavioral variant frontotemporal dementia (bvFTD) based on the Rascovsky criteria (Rascovsky et al., 2011). * Diagnosed with Major Depressive Disorder (MDD) according to DSM-IV criteria. Eligibility Criteria for Healthy Age-, Sex-, and Education-Matched Controls: * Mini-Mental State Examination (MMSE): Score \> 27. * Medical History: No history of neurological or psychiatric disorders. Exclusion Criteria: * MRI Contraindications: Standard contraindications to magnetic resonance imaging (e.g., pacemaker, metallic implants, claustrophobia). * Cognitive Barriers: Inability to comprehend study instructions. * Legal Restrictions: Individuals referenced in Articles L.1121-5 to L.1121-8 and L.1122-12 of the French Public Health Code.

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Conditions

The condition(s) this trial relates to.

behavioral variant of frontotemporal dementia dementia disease Lethargy major depressive disorder nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APATHY Behavioral variant frontotemporal dementia (BVFTD) Depression - major depressive disorder Disinhibition

Contacts and locations

Locations

  • Paris Brain Institute / ICM / Pitié-Salpêtrière Hospital AP-HP / CIC

    Paris, 75013, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.