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Teens with PCOS: do birth control pills help anxiety and depression?

NCT ID NCT07127458

Symptom relief Sponsor: Ege University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study measured how common anxiety and depression are in adolescents with polycystic ovary syndrome (PCOS). 42 teens took a combined oral contraceptive daily for six months. Researchers tracked changes in depression scores to see if the pill improved mood along with PCOS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
combined oral contraceptive (ethinylestradiol 30 µg + drospirenone 3 mg)
What this could lead to
If successful, this could show that oral contraceptives help ease anxiety and depression symptoms in teens with PCOS.
What could go wrong
This is a small, completed study with only 42 participants and no control group, so results may not apply to everyone. It also cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Aug 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 19 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 15 and 19 years * Diagnosis of adolescent polycystic ovary syndrome (PCOS) Exclusion Criteria: * Severe reading or comprehension difficulties * Severe hearing impairment * Current use of hormone therapy * Presence of a virilizing tumor * Major psychiatric disorders such as schizophrenia, bipolar disorder, or dissociative disorder

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PCOS (polycystic ovary syndrome)

Contacts and locations

Locations

  • Izmir Bakircay University

    Izmir, 35665, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.