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Can blood thinners be safer for stroke patients with hidden brain bleeds?

NCT ID NCT05032053

Disease control Sponsor: Xijing Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study follows 3,000 ischemic stroke patients who also have cerebral microbleeds — tiny spots of old blood in the brain. Researchers are tracking how different antithrombotic drugs (blood thinners) affect the number of microbleeds and the risk of future strokes or brain bleeds over one year. The goal is to find which medications are safest and to identify blood markers that could predict outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
antithrombotic drugs (blood thinners)
What this could lead to
If successful, this could help doctors choose safer blood-thinning medications for stroke patients who have tiny brain bleeds, reducing the risk of future strokes or bleeding.
What could go wrong
This is an observational study, not a controlled experiment, so it cannot prove cause and effect. Results may not apply to all patients, and individual risks vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 3,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population we observed are hospitalized patients with new cerebral infarction and met the inclusion criteria(without exclusion criteria). The method of consecutive participant sampling is used to collect the included population.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients diagnosed clinically as ischemic stroke; 2. Age ≥ 40 years; 3. Onset time ≤ 3 months; 4. Informed consent was signed. Exclusion Criteria: 1. Patients with symptomatic intracranial hemorrhage; 2. bleeding lesion \> 10 mm was found on SWI; 3. Vascular malformations, tumors, abscesses or other major non ischemic brain diseases were present; 4. There are contraindications for antithrombotic drugs use; 5. Serious systemic diseases; 6. Refusal to sign informed consent or poor compliance.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    16 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • 3201 Hospital

    RECRUITING

    Hanzhong, Shaanxi, China

  • 986 Hospital

    RECRUITING

    Xi'an, China

  • Ankang Central Hospital

    RECRUITING

    Ankang, Shaanxi, 725000, China

  • Department of Neurology, Xijing Hospital, Fourth Military Medical University

    RECRUITING

    Xi'an, Shaanxi, 710032, China

  • Gaoling District Hospital

    RECRUITING

    Xi'an, China

  • Gem Flower Xi'an Changqing Staff Hospital

    RECRUITING

    Xi'an, China

  • Hanzhong People's Hospital

    RECRUITING

    Hanzhong, China

  • No.215 Hospital of Shaanxi nuclear industry

    RECRUITING

    Xianyang, China

  • Tangdu Hospital

    RECRUITING

    Xi'an, China

  • The First Affiliated Hospital of Xi'an Medical University

    RECRUITING

    Xi'an, China

  • The First People's Hospital of Xianyang

    RECRUITING

    Xianyang, China

  • Xi'AN GAOXIN Hospital

    RECRUITING

    Xi'an, Shannxi, 710032, China

  • Xian Yang Central Hospital

    RECRUITING

    Xianyang, China

  • Yan'an People's Hospital

    RECRUITING

    Yan’an, China

  • Yan'an University Affiliated Hospital

    RECRUITING

    Ya'an, Shaanxi, China

  • Yulin No.2 Hospital

    RECRUITING

    Yunlin, Shaanxi, 719000, China

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