Brain insulin study reveals hidden side effects of antipsychotics
NCT ID NCT03741478
First seen Jun 01, 2026 · Last updated Jun 05, 2026 · Updated 2 times
Summary
This study looks at how a common antipsychotic drug (olanzapine) changes the way the brain uses insulin, which affects blood sugar and memory. Healthy volunteers will receive either the drug or a placebo, plus insulin or placebo nasal spray, to measure changes in glucose production and cognitive performance. The goal is to understand why antipsychotics often cause weight gain and diabetes, especially in young people.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Center for Addiction and Mental Health
Toronto, Ontario, M5T 1R8, Canada
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University Health Network - Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.