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Antibiotic side effects under the microscope in bone infection study

NCT ID NCT05927311

Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study followed 73 adults with bone or joint infections who needed antibiotics for at least 6 weeks. Researchers tracked how often side effects occurred, how severe they were, and whether they affected quality of life. The goal was to understand why some patients stop treatment early, which can lead to treatment failure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
antibiotics
What this could lead to
If successful, this research could help doctors choose antibiotics with fewer side effects, improving treatment completion and quality of life for patients with bone or joint infections.
What could go wrong
This is an observational study, not a treatment trial. It only measures side effects, so it won't directly lead to a new cure or therapy. Results may not apply to all infection types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

73 people

The number who actually took part.

Started

Aug 2023

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient over 18 years of age with an osteoarticular infection requiring antibiotherapy of 6 weeks or more

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient over 18 years of age * Microbiologically proven osteoarticular infection with or without material, requiring antibiotic therapy (single or multiple) of 6 weeks or more * Oral antibiotic therapy (minimum 4 weeks) Exclusion Criteria: * Opposition to data processing * Patient under guardianship or trusteeship

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Conditions

The condition(s) this trial relates to.

bacterial arthritis osteomyelitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone infection Joint infection

Contacts and locations

Locations

  • University Hospital

    Tours, 37044, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.