Emergency room study aims to improve diagnosis of septic arthritis
NCT ID NCT05341908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined 750 emergency patients with joint pain to find out which germs cause septic arthritis. Researchers compared standard lab cultures with a new PCR test to see which works better. The goal is to help doctors diagnose joint infections more quickly and accurately.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors diagnose septic arthritis faster and more accurately in the emergency room.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly help patients. Results may not change current practice immediately.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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750 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This is a prospective, multicenter, observational study being conducted at 9 EMERGEncy ID NET sites, Olive View-UCLA Medical Center, Los Angeles, CA; Temple University Hospital, Philadelphia, PA; University of Mississippi Medical Center, Jackson, MS; Valleywise Medical Center, Phoenix, AZ; Truman Medical Center/U. Missouri Kansas City, Kansas City, MO; Hennepin Medical Center, Minneapolis, MN, University of New Mexico Health Sciences Center, Albuquerque, NM; University of Iowa Hospital, Iowa City, IA; and Johns Hopkins Medical Institute, Baltimore, MD. These hospitals service a mostly urban and underserved population. Patients presenting to the above hospital emergency departments will be approached by study team members who meet the above eligibility criteria. The target enrollment for the study is 500 participants.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18 years and older; 2. diagnostic arthrocentesis in the emergency department (ED) or during hospitalization if admitted from the ED; 3. arthrocentesis and joint culture ordered; and 4. provide written consent in English or Spanish Exclusion Criteria: 1. Unable to consent or no legal authorized representative is available; or 2. prisoner or parolee
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Olive View-UCLA Medical Center
Sylmar, California, 91342, United States
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Other studies related to the condition(s) this trial covers.
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