Scientists probe acid 'Pain Channels' in arthritic joints
NCT ID NCT01867840
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study from France examined joint fluid from 20 people with arthritis to see if acid-sensing ion channels (ASICs) play a role in pain. Researchers wanted to find natural compounds that activate these channels during inflammation. The goal is to validate ASICs as targets for new pain treatments, but this was a basic science study, not a treatment trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new pain medications that block ASICs, offering relief for arthritis and other inflammatory conditions.
- What could go wrong
- This is a very small, early-stage lab study (20 people) that only looks at joint fluid samples. It does not test any treatment, so it may not lead to a usable drug.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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20 people
The number who actually took part.
- Started
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Jan 2018
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
(osteoarthritis, chondrocalcinosis, gouty arthritis, rheumatoid arthritis)
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * septic arthritis * gonarthrosis in push-inflammatory * microcrystalline arthropathies * chronic inflammatory rheumatism Exclusion Criteria: * refusal to participate in the protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Service de Rhumatologie
Nice, Nice, 06000, France
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Other studies related to the condition(s) this trial covers.
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