Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a special suture cut infection risk after joint replacement?

NCT ID NCT07322289

Disease control Sponsor: University of Miami Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study tests whether antibiotic-coated braided sutures work as well as standard monofilament sutures in patients with infected hip or knee replacements. Surgeons currently use weaker monofilament sutures in infected cases to reduce bacterial growth. If the coated braided sutures prove safe, surgeons could use stronger sutures without increasing infection risk. The trial will enroll 142 adults and track treatment failure at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
triclosan-coated braided suture
What this could lead to
If it works, surgeons could use stronger, easier-to-handle sutures without raising infection risk in joint infection surgeries.
What could go wrong
This is a small, early-stage trial (142 patients) comparing two suture types, not a new drug or cure. Results may not apply to all patients or infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 142 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Willing and able to provide informed consent * Primary Total Hip Arthroplasty or Total Knee Arthroplasty with Prosthetic Joint Infection Musculoskeletal Infection Society (MSIS) criteria * Prosthetic Joint Infection Treated with Debridement, Antibiotics, Implant Retention Acute Prosthetic Joint Infection: \<4 weeks since it was suspected/diagnosed Exclusion Criteria: * Staphylococcus aureus bacteremia * Mycobacterial, fungal, or parasitic infection * Concurrent infection needing prolonged Intravenous therapy * Septic shock/systemic illness needing IV therapy * Patients with severe immunosuppression (ex: chemotherapy, neutropenia, HIV, steroid use * Allergy to Triclosan * Pregnancy * Prisoners

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Debridement with prosthesis retention are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

periprosthetic joint infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Debridement with prosthesis retention Prosthetic joint infections of hip Prosthetic joint infections of knee Prosthetic-joint infection SUTURE

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Miami Health System

    Miami, Florida, 33132, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.