PROSTHETIC JOINT INFECTION

This study looks at whether taking probiotics alongside standard treatment can improve immune markers and recovery in people with hip or knee joint infections after replacement surgery. About 152 adults aged 18-90 who need surgery and antibiotics for their infection will take eit…

This study compares two ways to treat an infected artificial knee: a one-stage surgery that puts in a new knee right away with antibiotic cement, or a two-stage surgery that uses a temporary antibiotic spacer first. Both methods aim to clear the infection, but researchers want to…

This study tests whether a special gel applied to the skin during shoulder replacement surgery can reduce bacteria that might cause infections. It involves 60 adult male patients getting a first-time shoulder replacement. Researchers will compare infection-related bacteria levels…

This study tests if a new drug called PLG0206 can stop infections from coming back in people who have had a knee replacement and need surgery to treat an infection. About 240 adults will get either PLG0206 or a placebo during their surgery, along with standard care. Researchers w…

This study looks at whether certain blood and joint fluid tests can more accurately diagnose infections in people who need hip or knee replacement revision surgery. Researchers will compare these tests to standard methods and also check which approach is most cost-effective. The …

This study looks at how much fluid is needed to fully clean an infected knee replacement during a special surgery called DAIR. About 20 adults having knee revision surgery will take part. Doctors will use a blue dye to track contamination and take photos every 2 liters until the …

This study looks back at medical records of 150 patients who died in intensive care between 2018 and 2022 after being treated for a joint prosthesis infection. Researchers want to understand what these patients had in common and how their care was managed. The goal is to find way…

This study follows 50 adults with infected hip replacements to see how well different treatments work over time. Researchers will track infection clearance, complications, and treatment choices. The goal is to improve patient counseling and care quality, not to test a new drug or…