PROSTHETIC-JOINT INFECTION

This study is testing if a new drug called PLG0206 can help prevent a painful joint infection from coming back after knee replacement surgery. About 240 adults who have an infected artificial knee and are undergoing a specific cleaning procedure will receive either the study drug…

This study compares two types of temporary antibiotic spacers used to treat infections in artificial knee joints. Researchers will randomly assign patients to receive either a standard cement spacer or a more durable spacer made with real joint components. They will follow patien…

This study is testing whether adding probiotic supplements to standard care helps patients recover from infected hip or knee replacements. Researchers will check if probiotics improve blood markers of inflammation, reduce medical or surgical complications, and ease digestive issu…

This study aims to find the best combination of blood and joint fluid tests to diagnose infections in artificial hips and knees more quickly and accurately. It will involve 270 people who need surgery to fix or replace their artificial joint. The goal is to help doctors choose th…

This study is testing whether applying an antimicrobial gel to the surgical wound during shoulder replacement surgery can reduce bacteria that might cause infections later. Researchers are comparing the gel against no gel in 60 male patients undergoing shoulder replacement. They'…

This study looks back at medical records of 150 patients who died in intensive care units between 2018 and 2022 with serious joint infections around artificial hips, knees, or shoulders. Researchers will analyze patient information, treatments received, and outcomes to better und…

This study aims to track 50 patients with infected hip replacements over time to better understand which treatments work best. Researchers will collect detailed information on patient outcomes, complications, and recovery to improve future care. The goal is to build a clearer pic…