Could a gut drug help you heal faster after surgery?
NCT ID NCT02425774
First seen Mar 28, 2026 · Last updated Jun 21, 2026 · Updated 9 times
Summary
This study tested whether giving prucalopride before surgery can reduce inflammation and help the gut recover faster after pancreatic surgery. Thirty-one patients having part or all of their pancreas removed were given either prucalopride or a placebo. The goal was to see if the drug could mimic nerve stimulation to calm inflammation and speed up return of normal bowel function.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University hospitals Leuven
Leuven, Vlaams-Brabant, 3000, Belgium
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prucalopride
What this could lead to
If it works, this could lead to a new way to prevent or treat postoperative ileus, helping patients recover faster after abdominal surgery.
What could go wrong
This is a small pilot study with only 31 participants, so results may not apply to everyone. The drug's anti-inflammatory effect is still unproven, and side effects are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.