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Engineered immune cells take on returning blood cancers in early trial

NCT ID NCT01087294

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 25 times

Summary

This early-phase study tested a treatment for people whose B-cell cancers (like lymphoma or leukemia) came back after a donor stem cell transplant. Researchers took white blood cells from the original donor, genetically modified them to recognize and attack cancer cells, and gave them to 85 patients. The main goal was to check safety and find the right dose, with follow-up lasting up to 15 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • National Marrow Donor Program

    Minneapolis, Minnesota, 55401, United States

Conditions

Explore the condition pages connected to this study.