Can a postbiotic cream turn back the clock on aging skin?
NCT ID NCT07343544
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a cosmetic cream made with postbiotics (natural bacteria extracts) to see if it safely reduces wrinkles and age spots. About 45 women aged 35-60 with mild to moderate skin aging will apply the cream twice daily for 3 months. Researchers will measure changes in skin wrinkles, spots, and overall appearance using special cameras and skin tools.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female participants. * Age between 35 and 60 years. * All skin types (combination, oily, dry, and/or normal). * Skin condition: 50% sensitive skin and 50% normal skin. * Visible signs of facial skin aging (mild/moderate wrinkles and/or pigmentation spots). * Willingness to participate voluntarily and provide written informed consent. * Ability to understand the study objectives and procedures. * Good general health (physical and mental). * Availability to attend all scheduled visits at the research center. * Discontinuation of anti-aging products on the experimental area (face) at least 7 days prior to study start. * Commitment not to change facial hygiene routines during the study. Exclusion Criteria: * Pregnant or breastfeeding women. * History of allergy to cosmetic products and/or dietary supplements. * Known allergy or hypersensitivity to any component of the product. * History or current diagnosis of cancer. * Active skin diseases or infections in the experimental area. * Recent or planned surgical or aesthetic interventions in the experimental area Medical-aesthetic treatments on the face within the last 6 months (e.g., botulinum toxin, hyaluronic acid, laser, radiofrequency, HIFU, deep chemical peels, microneedling with actives). * Relevant dermatological conditions in the experimental area (eczema, psoriasis, allergic/contact dermatitis, etc.). * Use of topical or systemic medications affecting the skin (retinoids, antibiotics, corticosteroids) within the last 3 months. * Current or planned use of supplements that may affect skin health (collagen, antioxidant vitamins A/C/E, zinc, omega-3, oral probiotics/prebiotics). * Systemic diseases such as autoimmune disorders (rheumatoid arthritis, lupus, multiple sclerosis), chronic viral infections (HIV, hepatitis B/C), or severe metabolic diseases. * Use of any product other than the study product on the experimental area during the study. * Planned significant changes in health habits during the study (diet, physical activity, structured exercise programs). * Recent or planned changes in hormonal contraceptives. * Sun or UVA exposure during the study. * Participation in another clinical study involving the same experimental area * Application of any product on the experimental area on the day of study initiation. * Any medical condition, at the investigator's discretion, that may interfere with protocol adherence or participant safety.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a cream with good bacteria fix sensitive skin?