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New brightening peel shows promise for sun spots and uneven skin tone

NCT ID NCT07501000

Symptom relief Sponsor: Revision Skincare Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested a brightening treatment (a type of chemical peel) combined with a retinol serum and post-procedure cream on 11 healthy women aged 20 to 65 with moderate facial pigmentation from sun exposure or blemishes. Participants received four treatment sessions two weeks apart and were followed for 12 weeks. The goal was to see if the treatment safely improved skin pigmentation and texture.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Brightening treatment (chemical peel) with retinol serum and post-procedure cream
What this could lead to
If it works, this could offer a safe, clinician-applied option to reduce sun spots, blemishes, and uneven skin tone.
What could go wrong
This is a very small, early study with only 11 healthy women, so results may not apply to everyone. It also does not compare the treatment to a placebo or other options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

11 people

The number who actually took part.

Started

Oct 2024

Finished

Jan 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals in good general health (physical, mental, social well-being; not merely the absence of disease), based on medical history reported by the subject. 2. Individuals of Female biological sex. 3. Individuals between 20 to 65 years of age. 4. Individuals with Fitzpatrick skin types I - VI 5. Individuals of any race or ethnicity. 6. Individuals with moderate global facial Hyperpigmentation (score of 3 for darkness, and heterogeneity, and a score of 3 to 4 for area on the PIHASI scale). 7. Individuals with self-perceived facial pigmentation. Exclusion Criteria: 1. Individuals currently participating in or has participated in any other clinical study involving the face at another research facility or doctor's office within the past one (1) month. 2. Individuals with no self-perceived facial pigmentation. 3. Individuals diagnosed with known allergies to facial skin care products, moisturizers, or sunscreens. 4. Individuals who are nursing (breastfeeding), pregnant, or planning to become pregnant during the study according to subject self-report. 5. Individuals who currently smoke or have smoked (cigarette, e-cigarettes, etc.) within the past 5 years. 6. Individuals currently having or have a history of facial skin cancer within the past 5 years. Have or had cancer pertaining to any parts of the body and systems which in the opinion of the Investigator could interfere with the outcome of the study. 7. Individuals currently having or having a history of cold sores (Herpes Simplex) on the face.

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Conditions

The condition(s) this trial relates to.

Hyperpigmentation hyperpigmentation of the skin

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hyperpigmentation Post-inflammatory hyperpigmentation Skin ageing Skin roughness

Contacts and locations

Locations

  • Skin Wellness Dermatology

    Birmingham, Alabama, 35209, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.