New pain drug timing could speed recovery after gallbladder surgery
NCT ID NCT07566663
First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times
Summary
This study tests whether giving the pain drug Anrikefon before or during gallbladder surgery works better for reducing pain and helping recovery. 274 adults having laparoscopic gallbladder removal will receive the drug either 15 minutes before anesthesia or right after the gallbladder is removed. Researchers will track pain levels and recovery quality over 24 hours to find the best timing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Anrikefon
- What this could lead to
- If successful, this could show the best timing for Anrikefon to reduce pain after gallbladder surgery and improve recovery.
- What could go wrong
- This is an early-stage study with no phase, so results may not confirm benefit. The drug's effect on pain is still being explored, and individual responses may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 274 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ASA physical status classification I-III; 2. Age 18-65 years; 3. Scheduled for elective laparoscopic cholecystectomy; 4. Voluntary signed informed consent; 5. BMI between 18-28 kg/m²; 6. No history of general anesthesia surgery within the past 3 months. Exclusion Criteria: 1. Severe cardiovascular disease, respiratory disease, or psychiatric disorders; 2. Severe renal insufficiency; 3. Recent use of diuretics or compound medications containing diuretics; 4. Continuous use of opioid analgesics for more than 10 days within the past 3 months; 5. Use of medications with unknown half-life affecting analgesic efficacy within 14 days prior to randomization; 6. Pregnant women, lactating women, or those planning pregnancy in the near future; 7. History of hypersensitivity to study medications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100053, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common anesthetic stop Post-Surgery delirium in the elderly?
- Can a single drug dose curb opioid side effects after kidney stone surgery?
- Can a new Non-Opioid pill cut painkiller needs after throat surgery?
- Can zapping three acupoints rewire the brain to ease surgical pain?
- Can a triage checklist ease pain months after emergency surgery?
- Can a nerve block quiet the brain during gallbladder surgery?