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Can the ankle fully recover after donating a tendon for ACL repair?

NCT ID NCT07762989

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study follows 20 adults aged 18 to 55 who had ACL reconstruction using a peroneus longus tendon graft from their ankle. Researchers will measure ankle strength, balance, walking patterns, and joint position sense at 6-8 weeks, 3 months, and 6 months after surgery, comparing the donor ankle to the other ankle. The goal is to understand how well and how quickly the ankle recovers, which could inform future surgical and rehabilitation decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Anterior cruciate ligament reconstruction using a peroneus longus tendon autograft
What this could lead to
If successful, this could help surgeons understand how well the ankle recovers after using this graft, potentially improving surgical choices and rehabilitation protocols.
What could go wrong
This is a small observational study (20 participants) without a control group, so results may not apply broadly. It only measures recovery, not the effectiveness of the surgery itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 18 to 55 years who have undergone primary unilateral anterior cruciate ligament reconstruction using a peroneus longus tendon autograft as part of routine clinical care and are referred to the Sports Health Unit, Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, for postoperative rehabilitation and functional assessment. Eligible participants will be enrolled consecutively during the study period.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 55 years. * Unilateral primary anterior cruciate ligament tear confirmed by clinical examination and magnetic resonance imaging. * Primary anterior cruciate ligament reconstruction performed using a peroneus longus tendon autograft. * Able and willing to attend the postoperative assessments at 6-8 weeks, 3 months, and 6 months. * Written informed consent provided before study participation. Exclusion Criteria: * Multiligament knee injury. * Previous surgery on the index knee or donor ankle. * Pre-existing ankle instability or major foot or ankle pathology. * Neurological or neuromuscular disease. * Inflammatory or systemic disease that may affect the assessments. * Major lower-extremity deformity that may affect the assessments. * Unable to complete the postoperative rehabilitation program or scheduled follow-up assessments.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gazi University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Sports Health Unit

    Çankaya, Ankara, 06490, Turkey (Türkiye)

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