Can the ankle fully recover after donating a tendon for ACL repair?
NCT ID NCT07762989
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study follows 20 adults aged 18 to 55 who had ACL reconstruction using a peroneus longus tendon graft from their ankle. Researchers will measure ankle strength, balance, walking patterns, and joint position sense at 6-8 weeks, 3 months, and 6 months after surgery, comparing the donor ankle to the other ankle. The goal is to understand how well and how quickly the ankle recovers, which could inform future surgical and rehabilitation decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Anterior cruciate ligament reconstruction using a peroneus longus tendon autograft
- What this could lead to
- If successful, this could help surgeons understand how well the ankle recovers after using this graft, potentially improving surgical choices and rehabilitation protocols.
- What could go wrong
- This is a small observational study (20 participants) without a control group, so results may not apply broadly. It only measures recovery, not the effectiveness of the surgery itself.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults aged 18 to 55 years who have undergone primary unilateral anterior cruciate ligament reconstruction using a peroneus longus tendon autograft as part of routine clinical care and are referred to the Sports Health Unit, Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, for postoperative rehabilitation and functional assessment. Eligible participants will be enrolled consecutively during the study period.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 55 years. * Unilateral primary anterior cruciate ligament tear confirmed by clinical examination and magnetic resonance imaging. * Primary anterior cruciate ligament reconstruction performed using a peroneus longus tendon autograft. * Able and willing to attend the postoperative assessments at 6-8 weeks, 3 months, and 6 months. * Written informed consent provided before study participation. Exclusion Criteria: * Multiligament knee injury. * Previous surgery on the index knee or donor ankle. * Pre-existing ankle instability or major foot or ankle pathology. * Neurological or neuromuscular disease. * Inflammatory or systemic disease that may affect the assessments. * Major lower-extremity deformity that may affect the assessments. * Unable to complete the postoperative rehabilitation program or scheduled follow-up assessments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gazi University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Sports Health Unit
Çankaya, Ankara, 06490, Turkey (Türkiye)
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