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Tired ankles throw off balance – study reveals hidden risk for Sprain-Prone individuals

NCT ID NCT07273097

Knowledge-focused Sponsor: University of Ljubljana Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how fatigue in the ankle muscles affects walking balance in people with and without chronic ankle instability (CAI). Forty adults will walk on a treadmill at two speeds while gentle pushes are applied to their hips. Researchers will measure muscle activity and step patterns before and after tiring the ankle muscles to understand why people with CAI may be more prone to falls or re-injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited by convenience sampling from the general population and clinical settings.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for the healthy control group (no CAI): * Age between 18 and 45 years, * No history of injuries or surgical procedures to the lower limbs, * No peripheral or central neurological impairments. Inclusion criteria for the chronic ankle instability (CAI) group: * Age between 18 and 45 years, * No history of major surgical procedures on the lower limbs * No peripheral or central neurological impairments, * Diagnosed chronic ankle instability: * First ankle sprain occurred at least one year prior to testing, * At least three months since the most recent ankle sprain, * Subjective feeling of ankle instability - CAIT (Cumberland Ankle Instability Tool) score \< 24. Exclusion criteria for the CAI group: * Other pathologies of the ankle joint. * Acute pain

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Conditions

The condition(s) this trial relates to.

Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic ankle instability, cai

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Rehabilitation Institute Republic of Slovenia - URI Soča

    RECRUITING

    Ljubljana, 1000, Slovenia

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