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Does anesthesia choice affect immune cells during breast cancer surgery?

NCT ID NCT06151639

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at how two different anesthesia methods—general anesthesia and a nerve block called PECS block—affect certain immune cells in the blood of 50 women with breast cancer undergoing lumpectomy. The goal was to see if one method might be better for the immune system. The study measured changes in white blood cells, neutrophils, lymphocytes, and platelets before and after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
general anesthesia and PECS block (nerve block procedure)
What this could lead to
If it works, this could help doctors choose anesthesia methods that better support the immune system during breast cancer surgery.
What could go wrong
This is a small, completed study with only 50 participants, so results may not apply to all patients. It only looked at blood cell counts, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Aug 2022

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study was planned retrospectively. 50 patients who underwent wire localized lumpectomy for breast cancer treatment and diagnosis under general anesthesia (n=25) or PECS block (n=25) were found in hospital records.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with unilateral primary breast cancer * Are decided to undergo wire localized lumpectomy * Having a risk score of The American Society of Anaesthesiologists (ASA) risk score 1,2 and 3 * Should be over18 years old Exclusion Criteria: * Being allergic to the anesthetics * Opioid or steroid usage before the operation * Patients who could not reach a sufficient block level and required additional doses of analgesics

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

Contacts and locations

Locations

  • Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospita

    Ankara, Yenimahalle, 06200, Turkey (Türkiye)

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