Spinal vs. general anesthesia: which is safer for your heart during knee surgery?
NCT ID NCT07551648
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how spinal and general anesthesia change the heart's electrical activity in people having knee replacement surgery. Researchers measured heart signals before and after surgery in 140 adults. The goal was to see if one type of anesthesia affects the heart differently, which could help doctors choose safer options.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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140 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients undergoing elective total knee arthroplasty at a single center and managed with either spinal anesthesia or general anesthesia in routine clinical practice.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years and older * Patients scheduled for elective total knee arthroplasty * ASA physical status I to III * Patients undergoing surgery under spinal anesthesia or general anesthesia Exclusion Criteria: * Presence of a pacemaker * Known cardiac conduction abnormality * Technically inadequate preoperative electrocardiogram * Active preoperative electrolyte abnormality * Acute coronary syndrome * Heart failure * Bilateral knee arthroplasty performed in the same session
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Elazığ Fethi Sekin City Hospital
Elâzığ, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can the right anesthesia get knee replacement patients moving faster?