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Which anesthesia is better for obese patients? new study investigates

NCT ID NCT07611240

Knowledge-focused Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common anesthetics—propofol and sevoflurane—in 70 obese patients undergoing back surgery. Researchers will measure inflammation markers in blood samples taken before and after surgery to see which anesthetic causes less immune system disruption. The goal is to find the safer option for this patient group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Propofol and sevoflurane
What this could lead to
If it works, this could help doctors choose the best anesthesia for obese patients to reduce inflammation after surgery.
What could go wrong
This is a small, early-stage study that only looks at blood markers, not patient outcomes. Results may not apply to other surgeries or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 65 years * Patients scheduled for elective lumbar instrumentation surgery * Body mass index between 30 and 34.9 kg/m² * Patients who provided written informed consent Exclusion Criteria: * Known allergy to inhalational or intravenous anesthetic agents * Acute or chronic infectious disease * Autoimmune disease or immunodeficiency * Surgery within the last 3 months * Chronic anti-inflammatory or immunomodulatory drug use * Morbid obesity, defined as BMI \>35 kg/m² * History of malignancy or active cancer treatment * Renal failure, defined as GFR \<60 mL/min * Liver failure, defined as AST or ALT greater than 2 times the upper limit of normal * Diabetes mellitus, metabolic syndrome, or insulin resistance * Pregnancy or lactation * Neurological disease, including epilepsy, multiple sclerosis, or Parkinson's disease * Alcohol or substance abuse * Inability to comply with the study protocol or provide informed consent * Known allergy to study drugs (propofol, sevoflurane, remifentanil) * Emergency surgery

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lumbar spine surgery Obesity & overweight

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ataturk University

    RECRUITING

    Erzurum, 25000, Turkey (Türkiye)

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