Can a rheumatoid arthritis drug tame CAR-T's worst side effects?
NCT ID NCT04359784
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 27 times
Summary
This study tested whether anakinra, a drug used for rheumatoid arthritis, could prevent two serious side effects of CAR-T therapy: cytokine release syndrome (CRS) and nerve damage. 27 adults with B-cell lymphoma received anakinra alongside their CAR-T treatment. The goal was to see if this approach could make CAR-T therapy safer without reducing its effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
Conditions
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