PET scans may reveal hidden cause of brain bleeds
NCT ID NCT01619709
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 70 people who had a brain hemorrhage (bleeding stroke) to see if a special PET scan could tell whether the bleeding was caused by amyloid buildup in blood vessels or by high blood pressure. Participants received an injection of a radioactive tracer called Florbetapir, followed by a brain scan. The goal was to improve diagnosis of the underlying cause, which could guide future treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Florbetapir F 18 (PET imaging tracer)
- What this could lead to
- If successful, this could help doctors better distinguish between different causes of brain hemorrhage, leading to more targeted treatment.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. The imaging method may not prove useful in routine practice or change patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
70 people
The number who actually took part.
- Start date
-
Jan 2012
- Finished
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Jun 2017
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 90 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age : 40-90 years, * Non traumatic primary intracerebral hemorrhage during acute phase (less than 30 days from hemorrhage onset) confirmed on brain imaging (CT and/or MRI). * Correct visual, hearing and language functions to perform neuropsychological tests. * Written consent of patient Exclusion Criteria: * Secondary causes of intracerebral hemorrhage : vascular malformations (Arteriovenous malformation, intracranial aneurysm, Cavernous angioma, dural arteriovenous fistula), cerebral venous thrombosis, intracranial neoplasm, coagulopathy, vascularitis, Cocaine or alcohol use, Hemorrhagic ischemic stroke. * Pregnancy * Contraindication to MRI * progressive neoplasm * Cognitive impairment secondary to progressive neurological disease * Depression, * Drug addiction
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Service de neurologie
Toulouse, 31059, France
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Other studies related to the condition(s) this trial covers.
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