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Can a simple amino acid drink help elderly COPD patients keep muscle?

NCT ID NCT01173354

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 30 times

Summary

This study tested whether a special essential amino acid supplement (high in leucine) could help elderly patients with COPD build muscle protein better than a standard amino acid mixture. Thirty-four participants received a one-time dose of either supplement, and researchers measured changes in protein synthesis and breakdown. The goal was to see if targeting specific metabolic issues could improve muscle health in COPD.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

essential amino acid mixture (high leucine)

What this could lead to

If it works, this could point toward a nutritional supplement to help prevent muscle loss in elderly COPD patients.

What could go wrong

This is a very small, early study (34 people) looking only at short-term effects. It does not test long-term benefits or safety, so results may not lead to a practical treatment.

Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.