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Brain injury and ARDS: which breathing maneuver is safer?

NCT ID NCT02574169

First seen Jun 02, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This study compared two breathing techniques (CPAP and eSigh) in 18 patients with brain injury and acute respiratory distress syndrome (ARDS). The goal was to see which method better maintains oxygen levels in the brain without causing harm. The trial was terminated early, so findings are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UH Caen

    Caen, 140033, France

  • UH Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • UH Montpellier

    Montpellier, 34295, France

  • UH Nantes

    Nantes, 44093, France

  • UH Toulouse

    Toulouse, Midi Pyrénées, 31059, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alveolar recruitment maneuvers (CPAP and eSigh)

What this could lead to

If successful, this could help doctors choose safer breathing methods for patients with both brain injury and lung failure.

What could go wrong

The study was terminated early with only 18 participants, so results are very limited and may not apply to all patients.

Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome Respiratory Distress Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.