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Breathe away the nausea: new study tests nostril breathing for morning sickness

NCT ID NCT07378839

Symptom relief Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily breathing exercise called alternate nostril breathing can reduce nausea and vomiting in early pregnancy. One hundred pregnant individuals in their first trimester will either practice the breathing technique three times a day for a week or receive standard care. Researchers will measure changes in symptom severity using a standard nausea score.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Alternate nostril breathing (a breathing exercise)
What this could lead to
If it works, this could offer a simple, drug-free way to manage nausea and vomiting in early pregnancy.
What could go wrong
This is a small, early-stage trial with no blinding, so results may be influenced by placebo effects. The breathing exercise may not reduce symptoms for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant individuals aged 18 years or older * Viable pregnancy with a gestational age between 6 0/7 - 12 6/7 weeks of gestation, confirmed by last menstrual period or ultrasound * Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12) * Ability to understand and read English Exclusion Criteria: * Severe nausea and vomiting, defined as a PUQE score \>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy * Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD) * History of severe anxiety disorders affecting breathing patterns * Known deviated nasal septum * Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy

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Conditions

The condition(s) this trial relates to.

hyperemesis gravidarum Nausea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nausea Pregnancy emesis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Email: •••••@•••••

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