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New hope for Hard-to-Treat cancers: targeted drug enters human trials

NCT ID NCT06835569

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 31 times

Summary

This early-phase study tests a new drug called ALTA3263 in adults with advanced solid tumors (like pancreatic, lung, or colorectal cancer) that have a specific genetic change called a KRAS mutation. The main goal is to check the drug's safety and find the right dose. About 448 participants whose cancer has worsened after standard treatments will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Orlando, Florida, 32827, United States

  • Research Site

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Research Site

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Research Site

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Research Site

    RECRUITING

    New York, New York, 10016, United States

  • Research Site

    RECRUITING

    New York, New York, 10032, United States

  • Research Site

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Research Site

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Research Site

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Research Site

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Research Site #2

    RECRUITING

    San Antonio, Texas, 78229, United States

Conditions

The condition(s) this trial relates to.

carcinoma colonic neoplasm colorectal neoplasm lung neoplasm neoplasm Neoplasm Metastasis Neoplasms by Site non-small cell lung carcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.