Can listening tasks reveal hidden speech changes in ALS?
NCT ID NCT06828523
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study at Penn State University will have 1,300 listeners judge recordings of speech from people with ALS and healthy speakers. The goal is to see how different conversation tasks affect how clearly someone with ALS is understood. No treatment is involved; this is purely observational research to better understand speech perception.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help develop better ways to assess speech clarity in ALS, improving communication tools and therapies.
- What could go wrong
- This is an observational study with no treatment. Results may not translate to real-world communication or benefit participants directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * passing the remote hearing screening * having no known speech, language or neurological disorders per self-report * being a native monolingual speaker of American English * having no experience communicating with people with dysarthria * being between the ages of 18 and 65. Exclusion Criteria: * None - if volunteer meets the inclusion criteria, then they will be enrolled
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Speech Core, Pennsylvania State University
RECRUITINGUniversity Park, Pennsylvania, 16802, United States
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