ALS study reveals hidden sensory changes in the brain
NCT ID NCT03694132
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how amyotrophic lateral sclerosis (ALS) affects the brain's ability to process touch and other sensations, even when patients don't notice problems. Researchers used brain imaging and electrical recordings to compare 52 people with ALS and healthy volunteers. The goal was to find hidden sensory changes and link them to brain structure, not to test any treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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52 people
The number who actually took part.
- Started
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Nov 2018
- Finished
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Mar 2021
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ALS, MRC score ≥ 4 at least in one hand * Controls: no history of neurological disorders, right-handed Exclusion Criteria: * contraindication to MRI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hopital Pitie-Salpetriere
Paris, 75013, France
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Other studies related to the condition(s) this trial covers.
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