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Breakthrough: ALS may soon be diagnosed with a simple saliva test

NCT ID NCT05928416

First seen Apr 05, 2026 · Last updated May 01, 2026 · Updated 8 times

Summary

This study explores whether a simple saliva test can help diagnose Amyotrophic Lateral Sclerosis (ALS), a serious nerve disease. Researchers are analyzing genetic material in saliva from 653 people—some with ALS and some healthy—to find a unique signature for the disease. If successful, this could lead to faster, less invasive diagnosis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • C.H.U. de Saint-Étienne

    Saint-Étienne-de-Montluc, Pays de la Loire Region, 42055, France

  • CHRU Lille

    Lille, 59037, France

  • CHU Angers

    Angers, 49933, France

  • CHU Bordeaux

    Bordeaux, 33000, France

  • CHU Bretonneau

    Tours, 37044, France

  • CHU Caen

    Caen, 14000, France

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • CHU Dupuytren

    Limoges, 97042, France

  • CHU Montpellier

    Montpellier, 34295, France

  • CHU Nantes

    Saint-Herblain, Loire-Atlantique, 44162, France

  • CHU Nice

    Nice, 06100, France

  • CHU Rennes

    Rennes, 35000, France

  • CHU Strasbourg

    Strasbourg, Alsace, 67098, France

  • CHU Toulouse

    Toulouse, 31059, France

  • CHU de la Réunion

    Saint-Pierre, 97448, France

  • Hospices Civils de Lyon

    Bron, Rhône, 69677, France

  • Hôpital Cavale Blanche

    Brest, 29609, France

  • Hôpital de La Timone

    Marseille, 13005, France

  • Hôpital de la Pitié-Salpêtrière

    Paris, 75013, France

Conditions

Explore the condition pages connected to this study.