New combo therapy aims to boost breathing in ALS patients
NCT ID NCT05377424
First seen Feb 24, 2026 · Last updated May 22, 2026 · Updated 16 times
Summary
This study tests whether a medication called istradefylline, combined with short periods of breathing air with less oxygen (acute intermittent hypoxia), can improve breathing in people with ALS. Researchers will compare results from 40 adults with ALS and healthy volunteers. The goal is to see if this approach is safe and helps increase breath depth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinical and Translational Research Building
Gainesville, Florida, 32610, United States
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UF Health Jacksonville
Jacksonville, Florida, 32209, United States
Conditions
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