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Could an antioxidant shield the penis from damage after a painful erection?

NCT ID NCT07391709

Knowledge-focused Sponsor: Trabzon Kanuni Education and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study in 18 rats investigates whether alpha lipoic acid, a natural antioxidant, can protect penile tissue from damage caused by restoring blood flow after a prolonged painful erection (priapism). Researchers will measure various markers of oxidative stress and inflammation in blood and tissue. The goal is to see if this simple supplement might one day help prevent long-term harm in men who experience this condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
alpha lipoic acid
What this could lead to
If it works, this could point toward a treatment to prevent tissue damage from prolonged painful erections in humans.
What could go wrong
This is a very early animal study with only 18 rats. Results may not apply to humans, and the treatment may not be effective or safe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

18 people

The number who actually took part.

Started

Feb 2024

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 16 weeks

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: • Adult male Sprague-Dawley rats weighing 350-400 g. Exclusion Criteria: * Animals with congenital anomalies, active infection, or systemic disease. * Animals that died before completion of the experimental protocol.

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Conditions

The condition(s) this trial relates to.

priapism ischemia reperfusion injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Priapism Reperfusion injury

Contacts and locations

Locations

  • Karadeniz Technical University Experimental Animal Research Center

    Trabzon, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.