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Can a urine test help spot risky drinking in HIV-affected teens?

NCT ID NCT06903143

Knowledge-focused Sponsor: Centre for Infectious Disease Research in Zambia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This pilot study explores whether adding a urine biomarker test to standard alcohol screening can improve detection and treatment of harmful drinking among HIV-affected adolescents and young adults in Lusaka, Zambia. Sixty participants aged 16–24 will receive a brief counseling session and, if needed, a referral to more intensive therapy. Researchers will track how many complete each step and interview participants and staff to assess the program's feasibility and acceptability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Screening, brief intervention, and referral to treatment (SBIRT) program
What this could lead to
If successful, this approach could improve alcohol screening and reduce harmful drinking among HIV-affected youth in resource-limited settings.
What could go wrong
This is a small pilot study with only 60 participants, so results may not apply broadly. The program's effectiveness and feasibility are still being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Sep 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 24 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 16-24 years of age * Residing in Lusaka, Zambia * Meets definition of HIV-affected as evidenced as being involved in HIV testing and treatment and Adolescent Friendly Spaces Programs at the three sites (we will not ask adolescents direct questions about HIV during screening; see Recruitment section). Exclusion Criteria: • Unable or unwilling to provide informed assent/consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol

Contacts and locations

Locations

  • CIDRZ

    Lusaka, Lusaka Province, 10101, Zambia

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