Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a simple protein infusion prevent deadly Re-Bleeding in cirrhosis patients?

NCT ID NCT07395141

Disease control Sponsor: King George's Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether adding albumin to standard treatment reduces re-bleeding and death in adults with cirrhosis who have acute variceal bleeding. Sixty participants will be randomly assigned to receive either albumin for three days plus standard care, or standard care alone. The main outcomes are re-bleeding during hospitalization and at six weeks, as well as in-hospital mortality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Albumin
What this could lead to
If it works, this could show that adding albumin to standard treatment helps prevent re-bleeding and improves survival in people with cirrhosis and acute variceal bleeding.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Albumin is generally safe, but it may not provide significant benefit over standard care alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adult patients with acute variceal bleeding and cirrhosis presenting to Medical Gastroenterology department at KGMU, Lucknow, U.P. India. Exclusion Criteria: 1. Age \< 18 years and \> 70 years 2. Patients with portal vein thrombosis 3. Hepatocellular carcinoma 4. Non-cirrhotic portal fibrosis 5. Extrahepatic portal vein thrombosis 6. Patients who received albumin in the last one month 7. Patients who require fresh frozen plasma 8. Patients with heart failure 9. Patients with chronic kidney disease 10. Volume overload state

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Acute variceal bleeding are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cirrhosis of liver esophageal varices with bleeding Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute variceal bleeding Cirrhosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dr Sumit Rungta

    Lucknow, Uttar Pradesh, 206003, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.